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Ribavirin may cause a significant reduction in red blood cell count which can cause anemiaAnemia can worsen heart disease and may cause heart attacks which may lead to deathPeople who have a history of heart disease should not be treated with ribavirin1,2.

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Kidney or liver diseaseother than hepatitis Chepatitis B infectiona blood cell disorder such as hemolytic anemiaa lack of red blood cellshuman immunodeficiency virusHIV or AIDSdiabetesa pancreas disordersarcoidosisbreathing problemsa thyroid disordernew or worsening eye problemssuch as retinopathya history of heart diseasehigh blood pressureor a heart attacka history of depression or suicide attempta history of a liverkidneyor other organ transplantor if you have ever received treatment for hepatitis C that did not work well.

Ribavirin is a medication that is used in combination with other medications to treat hepatitis CHep CIt is sold by itself under the brand name Ibavyr and Moderiba.

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in study nr15961 described as study 6 in the pegasys package insert , patients with chc hiv were randomized to receive either pegasys 180 g sc once weekly qw plus an oral placebo, pegasys 180 g qw plus copegus 800 mg po daily or roferon -a interferon alfa-2a , 3 miu sc tiw plus copegus 800 mg po daily.

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